What is the best way to heal a open wound?

You get the most from this site when you provide detail about the health issue you raise. What wound, where, how big, what caused it, bleeding or not, filled with debris or not? Your short question could apply to an open chest wound or a mosquito bite. Please consider starting over and providing more detail.

It depends on the size shape and location of wound. Some wounds my require suturing to bring the edges together. In an otherwise unspecified superficial wound, apply triple antibiotic cream should help in controlling infection. If you get fever or the wound has a purulent discharge, it would be prudent to see a doctor.