A member asked:

29yo female, chronic nausea and loose stool associated with anxiety. doctor suspected ibs, ordered colonoscopy and other tests. all came back normal (incl iga, igg, panca) except fecal calprotectin 1177. is ibd still possible/likely?

2 doctors weighed in across 2 answers
Dr. Hiep Le answered

Specializes in Nephrology and Dialysis

Calprotectin level of 1,177 is not consistent with IBS (irritable bowel syndrome). This high level is consistent with an infectious etiology or inflammation. Negative colonoscopy rules out ulcerative colitis, not crohn's disease which may not involve the colon yet. Besides seeing a GI doctor you may need to see an infectious disease specialist as well if your GI symptoms persist.

Answered 9/21/2022

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It is not feasible to provide an opinion without additional history, physical examination may be some tests. It would be prudent to see your doctor to see if you may be depressed. Depression is treatable. Counter-intuitive as it may seem, exercise may help. Start with low intensity exercise such as walking and gradually increase the intensity as tolerated. Drink more water. Wish you good health!

Answered 9/22/2022

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