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A 45-year-old female asked:

What would cause fit + in a 45y female with hx of colorectal cancer in remission and hemorrhoid ligation done 6mo ago, last egd+colo in 11/2020 (1 tabular adenoma bx, erosive gastritis), cea 0.7, 2g/dl hgb drop in last 2mo w/o clear bleeding source?

2 doctor answers2 doctors weighed in
Dr. Hiep Le
Dr. Hiep Leanswered
Nephrology and Dialysis 43 years experience
If FIT is positive, source of blood loss is likely from the GI tract, especially you have iron deficiency anemia with that 2 gm Hb loss. Unfortunately, you will need both upper and lower endoscopic studies again. Bleeding from small intestine can happen but it is relatively rare.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Gurmukh Singh
Pathology 50 years experience
A positive FIT test means bleeding in the lower intestine. It does not say anything about what may be causing the bleeding. It is imperative that you consult your doctor.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Hiep Le
Dr. Hiep Le commented
Nephrology and Dialysis 43 years experience
Dr. Singh is correct and I was wrong when stating that FIT detects occult (human) blood in the whole GI tract. Yes, it only detects the occult, human blood in the lower GI tract.
Jun 15, 2022
Last updated Jun 15, 2022

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