Caffeine which may increase the amount of tizanidine in the system. One cup of caffeine contains 95mg on average, so 5 cups is 475mg (a large amount). It takes approximately 12-15 hours for caffeine to clear the system. If you have not taken Zanaflex before, you may also be experiencing a side effect on its own. Try taking a lower dose (2mg) every 8-12 hrs as needed or wait until caffeine is gone
Answered 5/29/2022
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