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A 21-year-old male asked:

How long after taking cipro (ciprofloxacin) can i have caffeine again. in large amounts? is a day after stopping a 3 weeks course long enough to be drinking alot of coffee? i heard there were very bad interactions between these two.

2 doctor answers2 doctors weighed in
Dr. Paul Grin
Pain Management 38 years experience
After 33 hours: The half-life of Cipro (ciprofloxacin) is about 4–6 hours in subjects with normal renal function is approximately 4 hours. Heavy daily caffeine intake, more than 500 - 600 mg per day may cause side effects. Thus, 400 mg is a maximum daily dose = 4 caps. Take care.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Alan Wartenberg
A Verified Doctoranswered
Addiction Medicine 51 years experience
Interaction moderate: cipro (ciprofloxacin) may increase the effects of caffeine, causing more jitteriness, tremor, anxiety and insomnia. These effects should less within 3-4 days of finishing, but not necessarily the day after. Large amounts of caffeine really aren't good for you, and I urge you to moderate your use.
Created for people with ongoing healthcare needs but benefits everyone.

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Last updated Jan 12, 2015

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