A member asked:

Why are some people abnormally sensitive to caffeine e.g. 1 can drink coffee b4 bed w/o prob but 1 is super hyper for 7 hours after drinking it?

A doctor has provided 1 answer
Dr. Geoffrey Rutledge answered

Specializes in Internal Medicine

If someone takes caffeine (or just about any stimulant) regularly, the body adapts and "gets used to it". There are detailed mechanisms that explain this, but the bottom line is if you haven't been exposed to caffeine or a related stimulant, you will have a much bigger reaction to it, compared to someone who takes caffeine regularly.

Answered Sep 15, 2020

5.2k views

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