Should methotrexate be the first drug use to treat moderate psoriasis? ive been using topicals only. i am ready to try systematic treatment. what would be the systematic drug with the least amount of side effects?

For best care for your psoriasis I recommend being evaluated, treated and followed by a skilled dermatologist who will he up to date with the latest advonces in the treatment of psoriasis.

If the topical medication‘s have failed, there are several systemic medication including methotrexate, Otezla, humira, Enbrel, etc. Choice of medicine depends on severity of disease and comorbidities(other medical problems a person have). Please discuss with your dermatologist or rheumatologist which will be the best option for you based on based on your disease activity and comorbidities.