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A 37-year-old female asked:

Cardiolipin antibody igm was high 29 u/ml. igg is not elevated, all other blood work was within limits. my doctor thinks this is not worrisome but isnt it a risk for blood clots?

1 doctor answer1 doctor weighed in
Dr. Hiep Le
Dr. Hiep Leanswered
Nephrology and Dialysis 44 years experience
Both you and your doctor are probably correct. In general, for the diagnosis of APS, titer of either IgM or IgG has to be at least 40. However, in selected patients with an especially high clinical suspicion of APS, a titer above 20 may be clinically significant. Either case, test needs to be repeated in 12 weeks for confirmation.
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Last updated Feb 2, 2022


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