A member asked:

I am a 38 year old female who have been diagnosed with mgus. my protein levels went from 1.0 to 1.2 in 3 months. should i be worried? how can i bring my protein levels down?

3 doctors weighed in across 3 answers
Dr. Clarence Grim answered

Specializes in Endocrinology

I usually assume that a lab test can vary by 10% between tests and is normal. 10% of 1 is 0.1 so above 1.1 may be high but double check with the lab and your local Drs. May just be lab error or day to day variation. There are many different proteins that are measured so need to know exact one. Check lab report for more details such as what in normal in women like you.

Answered 11/14/2021

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Dr. Hiep Le answered

Specializes in Nephrology and Dialysis

Unfortunately, you cannot bring it down by yourself. Lab result fluctuates a lot, the level could go up or down 10-20% with the fasting or non fasting blood. However, if the level goes up further in the next test, you may need to be treated by a hemato-oncologist. The term MGUS may be misleading. To us, kidney specialists, MGUS could be renal significance.

Answered 11/16/2021

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I agree with Dr. Le that you should be evaluated & followed regularly by a hematologist oncologist as MGUS can morph into multiple myeloma. Appropriate testing including checking for abnormal amounts & types of protein in urine will be carried out so that multiple myeloma or AL amyloidosis won't be missed now or in the future.

Answered 11/16/2021

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