A member asked:

My doctor put me on duloxetine for pain,im finding myself gaining weight,i have bad kidneys, stage 3.would it hurt to take something like naproxin 220mg a day.my sister had schizophrenia and the meds made her gain so much weight she died of from it?

A doctor has provided 1 answer
Dr. Hiep Le answered

Specializes in Nephrology and Dialysis

As a kidney specialist, I am against using naprosyn for chronic pain in patients with chronic kidney disease. You can ask your doctor for an alternative to duloxetine such as gabapentin or pregabalin although these meds can increase fluid retention in some susceptible people. Besides a direct nephrotoxic effect, daily use of naprosyn can exacerbate hypertension or cause stomach disease.

Answered 11/6/2021

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