A member asked:

Will doxycycline (always) exacerbate existing increased icp? and will it do so immediately?

2 doctors weighed in across 2 answers

I don't believe that the accurate incidence of elevated ICP in users of doxy is known, but studies have shown that if it occurs it will develop within 8 weeks. In one case report, a person on the acne medication, retinA, elevated ICP developed after one dose of tetracycline, which is the class of antibiotics doxy belongs to. This combination of meds must be avoided.

Answered 10/17/2021

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A number of antibiotics and even Vitamin A have been implicated as causing Benign Intracranial Hypertension, (Pseudotumor Cerebri), but often, endocrinological abnormalities have played a more impactful role. Not clear that, in presence of Pseudotumor, doxycycline would worsen, but suggest alternative antibiotic to be completely safe.

Answered 10/17/2021

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