A member asked:

Hi, i'm 29m with v leiden factor, 2 dvt's, varicose veins and on xarelto. am i at higher risk of developing complication du to neither covid-19 or it's vaccines? i want to get vaccinated but is it safe regarding my condition? thank you very much?

3 doctors weighed in across 2 answers
Dr. Hunter Handsfield answered

Specializes in Infectious Disease

Blood clotting complications are fairly common with COVID-19 infection, and Leiden V probably increases that risk. One vaccine (Astra Zeneca) has a small increased risk of thrombotic complications, but few or no reports for others (e.g. Pfizer, Moderna). Your thrombosis tendency is a reason to be vaccinated, not to avoid the vaccine. Check with your personal physician to be sure. Good luck.

Answered 10/3/2021

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Dr. Hiep Le answered

Specializes in Nephrology and Dialysis

I agree with Dr. Handsfield. Clotting disorder is one of major complications of Covid-19 infection so you are at increased risk if you are infected because of positive for Factor V Leiden. Besides that, you are taking Xarelto so you are somewhat protective from the very rare thrombotic adverse effect of Covid-19 vaccine(s).

Answered 10/1/2021

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