A member asked:

In regard to 4th gen ab/ag hiv testing, if you had no immune response at 81 days (ie no antibodies detected) wouldn't p24 protein still be detectable in that case?

2 doctors weighed in across 2 answers
Dr. Hiep Le answered

Specializes in Nephrology and Dialysis

If test is done early, p24 antigen can be positive but antibody test may still be negative at that time; however, by 81 days the antibody test should be positive if p24 antigen is positive or if antibody is negative, p24 antigen should also be negative.

Answered 8/12/2021

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To be sure, get a HIV nucleic acid test at 6 months after exposure.

Answered 8/12/2021

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