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Fairfax, VA
A 29-year-old male asked:

Is long term ppi safe? decades? i am 29, and have been on ppi for atleast 6-7 years. had linx surgery but still have gerd. i take dexilant 60mg daily. safe rest of my life? better medicine in the pipeline? i dont wanna do surgery again if not needed?

2 doctor answers3 doctors weighed in
Dr. Silviu Pasniciuc
Internal Medicine 27 years experience
More and more studies are revealing long term side effects of PPI’s that are influencing absorption of different nutrients by suppressing acidity indefinitely. They may create premises for colon infections and renal failure among others. The goal remains using the least amount and replacing them whenever possible. Your gastroenterologist is your best resource going forward.
Dr. Clarence Grim
Endocrinology 57 years experience
Gravity never sleeps. Elevate the feet of the heat of your bed on 8” blocks. ESP if you have any problem with GERD at night. If BMI over 25 work in losing weight as abd fat presses on stomach.
May 23, 2021
Dr. Mujjahid Abbas
Bariatrics 20 years experience
GERD is a symptom and underlying cause need to be addressed , if a hiatal hernia is causing it Vs obesity contributing towards it etc. PPIs do have side effects in the long term, known or unknown, side effects are there! Long term suppression of a natural protection given by nature i.e stomach acid ; isn’t good eventually. You need a good GI doc and Surgeon!

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Last updated May 27, 2021

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