A member asked:

Hi there i have been diagnosed with tb in the spine i have done a biopsy of the bone and it says necrisois is seen and necrotizing granulomatous inflamtion does this mean i have cancer?

5 doctors weighed in across 2 answers
Dr. Amrita Dosanjh answered

Specializes in Pediatric Allergy and Asthma

The infection may have injured the bone integrity. The biopsy report should be reviewed for details of AFB staining. If cultures were sent to determine if there is TB infection present, sensitivities to a specific combination of drugs provides additional details. Bone cancer may be detectable if present, but infection and damage are more likely.

Answered 3/31/2021

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The report, if cited fully, describes damage to the bone by inflammation, and the term "necrotizing granulomatous" would likely refer to tuberculosis as the mechanism. There is no mention of cancer, so have no clue why that is a concern. Suggest discussion with your doctors regarding their interpretation and recommendations for the next step.

Answered 3/30/2021

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