Splenomegaly: Portal vein hypertension can cause an enlarged spleen. Perhaps your doctor is just being careful to rule out other causes. If you PV hypertension is due to advanced liver disease e.g. cirrhosis, that in itself raises the risk of liver cancer. Your doctor is in by far the best position to answer these questions and surely would be happy to do so. Good luck.
Answered 2/21/2021
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