My wife has very high estrogen level she did have ovarian cancer which was removed she had blood tests the other day and her estrogen level were 2000?

Talk with your doc: As a gynecologic oncologist, i don't usually follow estrogen as a marker for ovarian cancer. There are a few rare exceptions (granulosa cell tumors). Estrogen is also made in fat cells. You and your wife should have a conversation with her doctor about why they are sending estrogen levels at all. Aromatase inhibitors are a group of drugs that prevent estrogen production and can be used to treat.