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A member asked:
Could you please tell me whether jak-2 overlap myeloproliferative/myelodysplastic disorder is familial?
A doctor has provided 1 answer
JAK2 mutation: JAK2 (Janus Kinase 2) mutations cause myeloproliferative neoplasm (MPN) in which those affected are at higher risk for blood clots and leukemia. New research reports show that while the JAK2 V617F mutation itself is not passed down from parent to child, there is an inherited genetic predisposition for developing this mutation and, therefore, MPN. Talk to your Dr about the details of your disease.
Answered 9/29/2020
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Related Questions
A member asked:
Is overlap myelodysplasticity myeloproliferative disorder a name for one disorder with common features of two disorders or the one blood disorder ?
3 doctors weighed in across 2 answers
A member asked:
Are any of (1) overlap myeloproliferative/myelodysplastictiy disorder (2) monoclonal B cell lymphocytosis or(3) monoclonal gammopathy ever familial?
A doctor has provided 1 answer
A member asked:
Could you please tell me whether a myeloproliferative DISORDER is the same thing as a myeloproliferative NEOPLASM?
A doctor has provided 1 answer
A member asked:
Could you please tell me whether there any hematologic malignancies in addition to or other than the myeloproliferative disorders/neoplasms? If so, are any of them common?
A doctor has provided 1 answer
A member asked:
The question is not about me I understand that an acute transformation of overlap myeloproliferative/myelodyplastictiy disorder is the terminal phase of the disorder But what is a blastic transformation of the disorder? Is it the same thing as an ac?
5 doctors weighed in across 2 answers
People also searched for:
Is it unusual (even if possible) for overlap myeloproliferative-myelodysplastic disorder to lower an elderly person's oral temperature below 36C for about 50% of his temp readings over 2 weeks? The temperatures are highly likely to be accurate.
A relative has an overlap myeloproliferative/myelodysplastic disorder. He has been told that if it changes into an acute transformation then it may be life-threatening. However, is there some other possible change that could ALSO be life-threatening?
Is it likely that the chronicity of overlap myeloproliferative-myelodysplastic disorder would by itself cause this rising CRP (30.5 mg/L 37.8; 54.3 ; 66.0; 110.0; 126.9; 148.5; 89.6; & 147.3)? It will be investigated bit I still desire an opinion now
85 year-old friend has for 2 weeks had his temp < 36C 19 times out of 34 readings. I don't understand this inconsistency. WBC is moderately hi & CRP very hi & going up. Could the temps be due to his overlap myeloproliferative-myelodysplastic disorder?
If a person has overlap myeloproliferative-myelodysplastic disorder which is causing an elevated WBC and a very high (and increasingly high) CRP, could antibiotics bring down the CRP even if there is no infection?
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