A 23-year-old female asked:
My parents were cousins & my brother had down syndrome. now i am too getting married to my cousin soon, are there any birth defect risks in our future babies, how to prevent those risks ?
2 doctor answers • 3 doctors weighed in
Pediatrics 46 years experience
Prevent=don't marry: Down syndrome is a random event & has nothing to do with their cousin status. We each have recessive genes to an estimated 3-5 potential metabolic problem like PKU and the closer a kinship, the more chance an offspring from that pairing would have a recessive genetic disease. This is highest if a parent fathers a child with a daughter, and the risk declines the further away the relationship goes
61 viewsReviewed Jul 16, 2020
Psychiatry 25 years experience
Reconsider?: I agree with Dr. Ferguson. Marrying one's cousin definitely brings increased genetic risks to off spring.
61 viewsReviewed Jul 18, 2020
Last updated Jul 18, 2020
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