A member asked:

Any specific things that translocation of the 3and 5chromosome could cause?

A doctor has provided 1 answer

Depends: Translocations vary in their impact. If it is balanced,(the swap leaves the recipient with a complete set of chromosome material,) they can appear & function normally. Problems will emerge when this "normal" person reproduces & an unbalanced set of chromosomes is transferred to a fetus. The loss or gain chromosome material can result in loss of pregnancy or birth defects.

Answered 6/4/2020

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Translocation or down syndrome--what is difference ?

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