A member asked:

I have been on pristiq & cymbalta for twenty years for anxiety. i read an article published in 2018 cumulative dementia risk-ncbi & nih antidepressants can increase risk of dementia. i am 66 and need to stay on the medicine. should i be worried?

3 doctors weighed in across 2 answers
Dr. Heidi Fowler answered

Specializes in Psychiatry

Anticholinergic med: There are a number of studies with similar titles. "Cumulative Antidepressant Use and Risk of Dementia in a Prospective Cohort Study". Most nonanticholinergic antidepressants used in late life aren't associated with ^ dementia risk. However Paroxetine may be an exception. Pristiq & Cymbalta don't fall into that class. So, please don't worry. Take care

Answered 5/24/2020

74 views

Thank

Not so clearcut. Epidemiological studies are notoriously unreliable in general and rarely provide a scientific breakthrough. Depression can be the presenting feature of Alzheimer's years prior to clinical dementia. There is not a convincing brain chemical change causing permanent dementia from Prisiq or Cymbalta. So, talk to your psychiatrist and get this objectified.

Answered 6/22/2021

0 views

Thank

Related Questions

Sponsored Content
HealthTap Medical Group does not endorse products or services. Sponsored content revenues support our mission to make health information free and accessible to all.Learn more