A member asked:

I have to be on snri for the rest of my life. if i take them for 35 years, will it lead to dementia? i take pristiq and had 4 episodes of depression.

A doctor has provided 1 answer
Dr. Heidi Fowler answered

Specializes in Psychiatry

Recurrent depression: I would recommend life-long antidepressant medication to a patient who had 4 major depressive episodes. It doesn't mean that the antidepressant would have to be an SNRI. "15,660 people reported to have side effects when taking Pristiq. Among them, 14 people (0.09%) have Dementia" per https://www.ehealthme.com/ds/pristiq/dementia/. That doesn't mean that Pristiq caused the dementia.

Answered 11/19/2018

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Does being on pristiq for thirty years cause dementia?

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