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A member asked:
I have been in n cymbalta now for ten years at 60 mg. i have read that it has a high anti-cholenergic effect. i am concerned about getting dementia?
A doctor has provided 1 answer
Cymbalta/duloxetine: (a potent inhibitor of serotonin and norepinephrine reuptake by nerve cells with little effect at cholinergic receptors) is approved for treatment of major depression and peripheral neuropathic pain associated with diabetic neuropathy. Speak with your prescriber if concerned about possible dementia. To reduce risk of developing dementia: healthy diet/weight, exercise, limit alcohol. Best regards.
Answered 6/11/2017
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