A 36-year-old female asked:
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is there any other possible explanation for a positive endomysial antibody iga and an elevated (>100) ttg iga, other than celiac disease? additionally, is it possible for food allergies to cause this elevation?

2 doctor answers
Dr. Shaban Faruqui
Specializes in Gastroenterology
SB bx is nessacary: Of all these tests, the EMA-IgA blood test is considered the most accurate blood test for celiac disease, meaning that if you have a positive result on the EMA-IgA, you very likely have celiac disease.All celiac disease blood tests require that you be on a gluten-containing diet to be accurate. Tissue Transglutaminase Antibodies (tTG-IgA) – the tTG-IgA test will be positive in about 98% of patient
Answered on Feb 23, 2020
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Dr. Amrita Dosanjh
35 years experience Pediatrics and Pediatric Pulmonology
Gluten elimination: If the level decreases with gluten elimination from the dief upon re testing, it is most likely that you have celiac disease. Tissue transglutaminase (tTG) IgA antibody is associated with glutensensitive enteropathies. Food allergies may also improve after elimination of the trigger and can be confirmed by a CAP blood test.
Answered on Feb 27, 2020
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