A member asked:

Is there any other possible explanation for a positive endomysial antibody iga and an elevated (>100) ttg iga, other than celiac disease? additionally, is it possible for food allergies to cause this elevation?

3 doctors weighed in across 2 answers
Dr. Shaban Faruqui answered

Specializes in Gastroenterology

SB bx is nessacary: Of all these tests, the EMA-IgA blood test is considered the most accurate blood test for celiac disease, meaning that if you have a positive result on the EMA-IgA, you very likely have celiac disease.All celiac disease blood tests require that you be on a gluten-containing diet to be accurate. Tissue Transglutaminase Antibodies (tTG-IgA) – the tTG-IgA test will be positive in about 98% of patient

Answered 2/23/2020

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Dr. Amrita Dosanjh answered

Specializes in Pediatric Allergy and Asthma

Gluten elimination: If the level decreases with gluten elimination from the dief upon re testing, it is most likely that you have celiac disease. Tissue transglutaminase (tTG) IgA antibody is associated with glutensensitive enteropathies. Food allergies may also improve after elimination of the trigger and can be confirmed by a CAP blood test.

Answered 2/27/2020

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