A 39-year-old member asked:
What do my celiac disease tissue transglutaminase iga/igg results mean?
1 doctor answer • 1 doctor weighed in

Dr. Michael P Vaughnanswered
Allergy and Immunology 36 years experience
Anti-transglutaminas: Antibodies that bind to transglutaminase could indicate the presence of celiac disease. This is a sugggestive test only. Negative testing does not definitively rule-out celiac dz and positive testing does not confirm the diagnosis. An intestinal biopsy would be the most helpful test.
Created for people with ongoing healthcare needs but benefits everyone.
5.8k viewsAnswered >2 years ago
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A 38-year-old member asked:
What do my celiac disease tissue transglutaminase test results mean?
1 doctor answer • 2 doctors weighed in

Dr. Charles Cattanoanswered
Gastroenterology 41 years experience
Depends...: If the test was performed to identify whether you have celiac disease, an unequivocally elevated ttg value is diagnostic for celiac disease. If you are IgA deficient, and the only ttg assayed was iga, you may miss a diagnosis of celiac disease due to a falsely negative result. If you have celiac disease, ttg can be used to assess how compliant you may be with strict dietary gluten avoidance.
Created for people with ongoing healthcare needs but benefits everyone.
5.9k viewsReviewed >2 years ago
Last updated Jun 26, 2012
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