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A 39-year-old member asked:

What do my celiac disease tissue transglutaminase iga/igg results mean?

1 doctor answer1 doctor weighed in
Dr. Michael P Vaughn
Allergy and Immunology 35 years experience
Anti-transglutaminas: Antibodies that bind to transglutaminase could indicate the presence of celiac disease. This is a sugggestive test only. Negative testing does not definitively rule-out celiac dz and positive testing does not confirm the diagnosis. An intestinal biopsy would be the most helpful test.

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A 38-year-old member asked:

What do my celiac disease tissue transglutaminase test results mean?

1 doctor answer2 doctors weighed in
Dr. Charles Cattano
Gastroenterology 40 years experience
Depends...: If the test was performed to identify whether you have celiac disease, an unequivocally elevated ttg value is diagnostic for celiac disease. If you are IgA deficient, and the only ttg assayed was iga, you may miss a diagnosis of celiac disease due to a falsely negative result. If you have celiac disease, ttg can be used to assess how compliant you may be with strict dietary gluten avoidance.
Last updated Jun 26, 2012


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