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Cedar Springs, MI
A 60-year-old female asked:

Both thumb joints at wrist are sore, one worse than the other. blood test shows rf of 25, sedimentation of 21, ana negative, crp negative, wbc 2.1....should i be concerned about ra?

2 doctor answers2 doctors weighed in
Dr. Gurmukh Singh
Pathology 49 years experience
Osteoarthritis: The information you provided suggests osteoarthritis rather than RA. You may take acetaminophen for pain, not more than 4 gm/day and no alcohol. Visit this site for info on this topic: https://www.arthritis.org/diseases/osteoarthritis
Dr. Hunter Handsfield
Infectious Disease 53 years experience
Rheumatoid arthritis: Your symptoms and RF test result are consistent with rheumatoid arthritis. Your quite low WBC count also is concerning, perhaps more important. It is peculiar to have moderately elevated erythrocyte sedimentation rate (ESR 21) but apparently normal C reactive protein (CRP). Follow up with the doctor who ordered the tests. If s/he isn't a rheumatologist, consider referral to one. Good luck.

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Last updated Jan 20, 2020

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