A member asked:

My wife has been having joint pains and a gets a red rash across her nose and cheeks. she has had an anf test for lupus which came back 1:80 titer. we were told anything below 1:80 is taken as negative. can this change to a positive reading later on?

A doctor has provided 1 answer
Dr. Silviu Pasniciuc answered

Specializes in Internal Medicine

Yes: Anf or antinuclear factor is rather nonspecific and it can change in time. Her symptoms are suggestive for the lupus spectrum of autoimmune diseases and further specific tests will likely be needed under the direction of a rheumatologist.

Answered 1/8/2020

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