What is the average time frame from gerd to going to barretts esophagus to going to barretts esophagus with high grade dysplasia?

Progression time: While barrett's esophagus is a risk factor for dysplasia. There are other factors that can lead to increase the risk: endoscopic factors, aging, male gender, obesity, and smoking. Overall, the risk of progression to the endpoint of adenocarcinoma is approximately 0.12% to 0.43%/year and for the combined endpoint of high-grade dysplasia/adenocarcinoma in the range of 0.26% to 0.63%/year.