A member asked:

I took spironolactone 100mg per day for a week to reduce my total body water and then stopped for a week and then resumed same dosage after a week. will that dosage for that length of time affect my testesteron levels and affect my muscles strength?

A doctor has provided 1 answer
Dr. Charles Turck answered

Specializes in Pharmacology

Unclear: Spironolactone does block some effects of testosterone and other chemicals in its class (called “androgens”). However, a number have suggested no change in the testosterone present in the body. There does not appear to be evidence suggesting that spironolactone decreases muscle strength.

Answered 9/20/2019

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