India
A 23-year-old female asked:
Can spironolactone help with water retention caused due to high estrogen levels?
1 doctor answer • 1 doctor weighed in

Dr. Jesse Krakaueranswered
Endocrinology 47 years experience
Yes: B"sd
spironolactone was actually developed as a diuretic - it has a hormonal mechanism of action blocking the adrenal salt retaining hormone aldosterone. It is in fact a very mild diuretic and anti-hypertensive - except when aldosterone is abnormaly high. In endocrinology we exploit a side property which is blockade of testosterone action on the skin - used for hirsuitism, acne.
Created for people with ongoing healthcare needs but benefits everyone.
1.6k viewsAnswered >2 years ago
Last updated Aug 8, 2016
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