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A 23-year-old female asked:

Can spironolactone help with water retention caused due to high estrogen levels?

1 doctor answer • 1 doctor weighed in
Dr. Jesse Krakauer
Dr. Jesse Krakaueranswered
Endocrinology 47 years experience
Yes: B"sd spironolactone was actually developed as a diuretic - it has a hormonal mechanism of action blocking the adrenal salt retaining hormone aldosterone. It is in fact a very mild diuretic and anti-hypertensive - except when aldosterone is abnormaly high. In endocrinology we exploit a side property which is blockade of testosterone action on the skin - used for hirsuitism, acne.
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Related questions

A 57-year-old female asked:
I have hyperaldosteronism. I take spironolactone, potassium and hctz. Strong family history of breast cancer worries me with estrogen dominance side effect of spironolactone. With no evidence of adrenal mass should I still get adrenal vein sampling?
1 doctor answer • 1 doctor weighed in
A 32-year-old female asked:
I took Spironolactone 100mg per day for a week to reduce my total body water and then stopped for a week and then resumed same dosage after a week. Will that dosage for that length of time affect my testesteron levels and affect my muscles strength?
1 doctor answer • 1 doctor weighed in
A 30-year-old female asked:
Can a diuretic (Spironolactone 100 mg) dehydrate you despite drinking lots of water, in a way that your body thickens your mucus and cause laryngitis?
1 doctor answer • 1 doctor weighed in
A 45-year-old female asked:
I have been taking spironolactone for over 2 years for hormonal acne. I reduced my dosage for a couple of weeks and quit taking it altogether. Two days later, I am retaining 10 lbs of water. It's quite uncomfortable. How long is this going to last?
1 doctor answer • 1 doctor weighed in
A 28-year-old female asked:
Gained 2-3 lbs after stopping spironolactone for acne. Could this be water weight? What can I do to get rid of this? Already drinking 90 oz of water.
2 doctor answers • 7 doctors weighed in
Last updated Aug 8, 2016

Found in:

Female health›Water retention›Estrogen

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