A member asked:

I know water pills can be prescribed together, but is taking them(furosemide, aldactone, lisinopril and clopidogrel) separately at different times a better option? and i do get diarrhoea, tiredness climbing uphill in the midst of taking them.

A doctor has provided 1 answer

Maybe: Furosemide & aldactone are both considered “water pills” but clopidogrel is a type of blood thinner & lisinopril is an ACE inhibitor not a water pill per se. If furosemide & aldactone & lisinopril are all taken together, that could lower the blood pressure enough to cause some fatigue, so perhaps best to take the furosemide & aldactone in the am & the lisinopril in the evening before bedtime.

Answered 6/11/2020

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