A member asked:

19 days ago i switched from ssri fluoxetine to sertraline as fluoxetine was no longer working (been on it 7 years at 60mg) and am now experiencing nausea, cramps and diarrhea quite badly. is this normal. should i stop sertraline (on 50mg)?

8 doctors weighed in across 2 answers
Dr. Louise Andrew answered

Specializes in Emergency Medicine

No, it's not: normal and you could be having a reaction to the new medicine or the two medications mixing in your system . Ask the person who switched your medicines what to do, please.

Answered 5/1/2019

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Fluoxitine: If you "switched" from fluoxetine to sertraline without a gap of 10-14 days, the fluoxetine was still in your system, and added similar ingredients to the new SSRI, which can cause the symptoms described. There are SSRI's with a shorter half-life, but by now ("19 days") the fluoxetine should be gone and the symptoms should be decreasing. If not, get a change in SSRI's from your physician.

Answered 5/6/2019

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