A member asked:

Experiencing breakthrgh depression after being on pristiq 100mg for 5 yrs. dr. switching me to vilazodone,10mg, (20mg, after 1mo.)how (soon)can i transition from ssri to the snri with the least chance of being w/o rx in my systm,causing more deprssn?

A doctor has provided 1 answer

Switching from one antidepressant to another is a very complex procedure. A washout period, during which you're not on any medication, makes it potentially dangerous as reemergence of depression is a serious concern. A psychiatrist, who knows your history & current status, would have to approve the transition and closely supervise the transition.

Answered 12/5/2022

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