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A 36-year-old female asked:

Can i take excedrin extra strength in the morning for a migraine if i took topamax 25mg at bedtime the night before?

1 doctor answer1 doctor weighed in
Dr. Vahe Yetimyan
General Practice 51 years experience
You better not : Excedrin decrease the sedation that topamax provides . Also topamax decrease the blood level of tylenol by increasing destruction of tylenol in the liver and by doing so it can possibly damage the liver. Consult to your doctor.

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Last updated Dec 23, 2020

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