A member asked:

I'm currently taking 2 prevacid (lansoprazole) in the morning i also have a horrific headache which i now believe to be a migraine is it ok to take excedrin migraine?

8 doctors weighed in across 2 answers
Dr. Michael McFadden answered

Specializes in Physical Medicine and Rehabilitation

It should be.: Excedrin contains aspirin, acetaminophen, and a significant amount of caffeine. If you don't have a significant history of peptic ulcers or poorly controlled blood pressure you should be fine. Be aware that frequent use of Excedrin will likely result in rebound headaches when you don't take it, i.e, caffeine withdraw headaches. Cheers!

Answered 4/24/2015

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Excedrin and PPI: There is no significant interaction between Excedrin and prevacid (lansoprazole). It is OK to take both.

Answered 3/1/2019

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