What oxygen flow rate to use for migraine headaches excedrin works but causes rebounds headaches and i tried topamax (topiramate) which cause hands to turn purple.

High: Oxygen is traditionally used for the treatment of cluster headaches but may be helpful for migraine. You want to use a high (12-15l/min) flow with a close-fitting non-rebreathing mask. Check with your dr. For their ok as there may be situations where you shouldn't use o2.

More common for: Cluster headaches rather than migraines, very different headaches. The norm starts around 2 liters and can go up to 12, but oxygen therapy is not benign and certain health issues can be exacerbated by increased o2 such as types of COPD or narcotics over medication. Be safe and consult your physician, discuss types of headaches with a specialist to make sure you have correct diagnosis.

Not likely: Used for cluster headaches rather than migraines, very different headaches.