A member asked:

Seroquel 400mg helps me just as much as risperidone 1mg. which of these two options is safer in terms of long term se? esp. ref. to extrapyramidal se.

A doctor has provided 1 answer
Dr. Heidi Fowler answered

Specializes in Psychiatry

SGA's: Second-generation antipsychotics (SGA’s) differ wi Extrapyramidal side effects (EPS). 1 meta-analysis showed that “risperidone resulted in more use of antiparkinson medication and thus showed more EPS than clozapine, olanzapine, quetiapine, and ziprasidone.” Quetiapine generic for Seroquel. (REF: Second-Generation Antipsychotic Drugs and Extrapyramidal Side Effects: A Systematic Review and Meta-

Answered 9/23/2018

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