A member asked:

If i take topamax early in day can i still occasionally take doxylamine (unisom) to sleep at night?

A doctor has provided 1 answer
Dr. Al Hegab answered

Specializes in Allergy and Immunology

Just be cautious: as the combination may increase risk of CNS depression, despite being spaced out, the topamax has a long half life, i.e. it stays longer in your body, and the doxylamine stays half as much. Good that you asked, always exercise caution with multiple medications.

Answered 7/7/2018

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