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Carrollton, GA
A 24-year-old male asked:

Is it safe to take 2 unisom for sleep instead of just the recommended 1? (they're 25mg doxylamine succinate) 1 doesn't work for me. tried benadryl (diphenhydramine) too

1 doctor answer3 doctors weighed in
Dr. John Chiu
Allergy and Immunology 59 years experience
Check with doctor: Although it is probably OK to double up on the dose, each person is different and perhaps the drug is not the best one for you and may not work even with doubling the dose. The current trend is to cut the dose down instead of raising it as in the case of Ambien (zolpidem). A sleep study may be helpful if this is a chronic issue.
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Dr. Anne Phelan-adams
A Verified Doctor commented
A US doctor answered Learn more
I agree with Dr. Chiu. Doxylamine is an antihistamine similar to diphenhydramine (benadryl). The makers are taking advantage of its common side effect, sedation, to market it as a sleep aid, but tolerance to this effect occurs after a few days of use.
Sep 25, 2014
Last updated Sep 7, 2018
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