Not really: Very low LDL cholesterol levels (less than 40) can occur genetically (hypobetalipoproteinemia), in which case such low values are present from birth, or in response to medical therapies. In both settings individuals have normal development, sexual function, and show no specific adverse effects. Low levels are sometimes noted due to severe illness (cancer, etc), but that is a different issue.
Answered 12/9/2013
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