A member asked:

Taking panadeine extra (15mg codeine+500mg) max daily dose for pain for 2 years and have been prescribed zoloft 50mg , seretonin syndrone a concern?

A doctor has provided 1 answer

Speak to prescriber: according to drugs.com, sertraline can reduce the effectiveness of codiene at time necessitating and increased dose of pain med. Definitely something you would want to discuss directly with prescriber, no concern for serotonin syndrome.

Answered 1/30/2020

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