A member asked:

A doctor on here said that zoloft (sertraline) can decrease the efficacy of tramadol. if so what drug could i use instead, but not codeine ?

A doctor has provided 1 answer
Dr. Howard Shapiro answered

Specializes in Internal Medicine - Nephrology & Dialysis

Other opiates: opiates can increase the effect of Zoloft (sertraline). Rarely, the two types of drug in combination can cause the serotonin syndrome with flushing fast heart rate and requires stopping both drugs immediately. You need to discuss alternate analgesics with your pain management specialist

Answered 11/14/2019

3.7k views

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A member asked:

Does Zoloft (sertraline) reduce effect of tramadol ?

A doctor has provided 1 answer

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