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Berkeley Township, NJ
A 22-year-old member asked:

What are the chances of severe serotonin syndrome if i take two 5/325 percocets while i am on 20 mg prozac and 50 mg zoloft (sertraline)?

1 doctor answer2 doctors weighed in
Dr. Edward Kuhnley
Child Psychiatry 46 years experience
These medications:: Prozac, Percocet and Zoloft (sertraline) have a moderate degree of interactive risk including risk of serotonin syndrome when taken together. Zoloft (sertraline) and Prozac are not necessary together though your prescriber may have a reason for it. Please consult your prescriber regarding this and the mixture of medications. Best regards for relief.
Last updated Apr 20, 2016

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