A member asked:

My spinal specialist prescribed me 10mg flexril to take at night. i'm also on 100mg zoloft but i take that in the mornings. is it okay to take both of these of they are taken at separate times? worried about serotonin syndrome?

2 doctors weighed in across 2 answers
Dr. Hiep Le answered

Specializes in Nephrology and Dialysis

It is a rare interaction so you can use this combination. It's good that you pay attention to this serious side effect so you just use them but watch for the symptoms of this syndrome then you can stop them on time.

Answered 4/16/2022

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Serotonin syndrome is quite rare and usually presents after overdoses or ingestion of unusually large amounts of provocative medications. Your dosing is modest at most, and it would be unique for your pills to afflict you. But since you worry, it is best to be proactive and discuss your concerns with the prescribing doctors.

Answered 4/20/2022

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