A member asked:

I just started taking wellbutrin 100mg every 12 hours 4 months ago and adderall xr 10mg starting today and i can't sleep can i take benadryl 25mg?

2 doctors weighed in across 2 answers
Dr. Al Hegab answered

Specializes in Allergy and Immunology

Be careful : Adding Benadryl to these two drugs isn't a problem, the problem is adding Welbutrin to Adderall , the two drugs need to be monitored carefully, inability to sleep won't be helped by Benadryl, kindly see / call your doctor for advice re adjusting your medications, good that you asked, always exercise caution with multiple meds, best wishes

Answered 6/17/2017

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Dr. Heidi Fowler answered

Specializes in Psychiatry

Med combo.: Talk with your prescribing physician about your insomnia. Wellbutrin can be stimulating. I usually recommend my patients take doses around 8 hours apart so that the second dose is not in the evening. Adderall is a stimulant - so recommend taking it early in the morning. Benadryl can be used with this. Also used good sleep hygiene.

Answered 6/18/2017

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