Up to 5 wks: It is difficult to determine the exact duration prozac will stay in the system, because people metabolize prozac at different rates. The longest it would probably stay in the system is 5 wks, (this is the "safe" washout time when there is no risk for drug interaction with MAO inhibitors.). Prozac has a half life of 7-9 days (pretty large margin there). but that does not mean it is out in 14-18 d.
Answered 7/7/2018
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