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A 36-year-old member asked:

How long approximately does it take for prozac (fluoxetine) to get out of your system totally?

1 doctor answer2 doctors weighed in
Dr. Alan Ali
Dr. Alan Alianswered
Psychiatry 33 years experience
Prozac (fluoxetine): Has half-life of up to 72 hours, so that multiplied by 5 means that it can stay in your system for up to 2 weeks or so.

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Similar questions

A 22-year-old female asked:

I took 20mg of Prozac (fluoxetine) for 4 days.. I have been off of it for 3 days.. How long does it take to get out of my system?

4 doctor answers6 doctors weighed in
Dr. Danny Westmoreland
Family Medicine 37 years experience
Should be gone: There would be trace but if you only took 4 doses then it should be pretty much cleared.
A 37-year-old member asked:

How long does 10mg of Prozac (fluoxetine) take to get into your blood system to feel effects?

1 doctor answer6 doctors weighed in
Dr. Mark Reynolds
Psychiatry 34 years experience
Prozac (fluoxetine): The time to onset of action of an antidepressant, including prozac, (fluoxetine) depends upon a number of factors including the condition being treated. That being said, you can generally expect one to two weeks to start to notice the clinical effect and 4-6 weeks to safely evaluate the full effect of any particular dose in the treatment of depression. Side effects, if present, can be experienced sooner.
CA
A 37-year-old member asked:

How long will it take for Prozac (fluoxetine) to leave my system?

1 doctor answer1 doctor weighed in
Dr. Donald Hazlett
Psychiatry 55 years experience
Quite a while: Prozac (fluoxetine) taken over a period of three or more months, then stopped, can show the presence of fluoxetine for five or more weeks. Prozac has both a right and left isomer (like looking at yourself in the mirror and raising your hand and watching your raised r hand appear to be your l hand). Breakdown of fluoxetine yields nor-fluoxetine which lasts 2 x as long in the body as fluoxetine.
A 45-year-old member asked:

How long does it take for Prozac (fluoxetine) to become effective?

1 doctor answer8 doctors weighed in
Dr. Steven Reidbord
Psychiatry 37 years experience
3 weeks or more: Most ssris start to show effectiveness against depression about 2 weeks after starting them. Prozac (fluoxetine) is about 1 week slower due to its long half-life (it takes longer to reach a steady blood level). So a good estimate is about 3 weeks. But everybody's different; some people feel better faster, others need to wait longer. Also, improvement is gradual, it doesn't become "effective" all at once.
Last updated Apr 30, 2017

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