A member asked:

Scared hysteroscopy/biopsy on 3/12 no hyperplasia/cancer put on prometrium (micronized progesterone) 2 months ago day 6 cycle 6mm this one day 4 is 12 mm how likely cancer now& why meds not working?

5 doctors weighed in across 2 answers
Dr. John Kirk answered

Specializes in Obstetrics and Gynecology

Very low: With a negative biopsy for both hyperplasia and cancer very unlikely that you have cancer despite the continued symptoms. However, it is not impossible. There is a small percentage chance perhaps 2-4% that a small cancer or hyperplasia was missed. Make sure you have follow up and consider doing a repeat ultrasound in six months as well as a biopsy if still bleeding to assess the uterine lining.

Answered 10/19/2016

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Very very unlikely: Lining in a premenopausal patient us normal up to ~25 mm at certain phases of cycle. The 5mm rule only applies to postmenopausal patients. You appear to not be obese. Smoking and diabetes are also risk factors.

Answered 1/5/2019

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