Is there an interaction with taking prozac (fluoxetine) and sinimet?

Probably OK: Prozac (fluoxetine) is a mood/depression medication that works on serotonin. Sinemet is a medicine most commonly used for parkinson disease that works primarily on dopamine. There are always possible interactions from two medications, but these two are used together in many patients without problems.

Check: You can use a drug interaction checker whenever you have questions about drug-drug interactions or drug - food interactions. Here is one option (Drugs.Com): https://www.drugs.com/drug_interactions.php Your pharmacist is also an excellent source of information.