What are the interactions between prozac (fluoxetine) and adipex?

Do not combine: IF you look at the FDA approved prescribing information for adipex, it clearly warns against combining the two due to serotonin syndrome risk (abnormal jerks, increased reflexes, temperature, confusion, sweating, elevated heart rate and BP, seizure risk). Prozac (fluoxetine) also blocks an enzyme that many medicines rely on for their own metabolism and can sometimes affect blood levels that way.